Transmission electron micrograph of a vacuole from a sertraline-treated sac1? mutant cell. The vacuolar membrane is moderately crenated. (25,000X). This image is part of a group of yeast vacuole images (CIL:40437-40448).
This group of images contains representative whole-cell images and high-magnification zooms of organelle structures of interest. All cells were grown in liquid rich media (YPD pH6.5) at 30C with aerated shaking, and cultures were sampled in mid-logarithmic phase. Treated cells were exposed to 60µM antidepressant sertraline (Zoloft®) for 45 minutes.