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*CIL – Cell Image Library accession number. Please use this to reference an image.

CIL:37224*  Cite 

Transmission electron micrograph of nerve cells at the thigh muscle motor end plate. The motor end plate is the highly-excitable region of muscle fiber plasma membrane responsible for initiation of action potentials across the muscles surface and ultimately causing the muscle to contract. Note that this very early (1953) micrograph is primarily of historical interest since it pre-dates glutaraldehye fixation which was introduced in the early 60's and is considered essential for adequate nerve tissue preservation. Examples of nerve tissue micrographs prepared in 1965 are CIL:37218, CIL:37219 and CIL:37220. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

Technical Details

Original 3.25 in. x 4 in. lantern slides were scanned at 600dpi. Original magnification x33,500.

Biological Sources
Cell Type
Cellular Component
neuromuscular junction
Biological Context
Biological Process
skeletal muscle contraction
Sanford Palay
George E. Palade EM Slide Collection
Digital Object Identifier (DOI)
Archival Resource Key (ARK)
Grouping This image is part of a group.
Image Type
recorded image
Image Mode
transmission electron microscopy (TEM)
Parameters Imaged
electron density
Source of Contrast
differences in adsorption or binding of stain
Visualization Methods
osmium tetroxide
Processing History
unprocessed raw data
Sample Preparation
chemically fixed tissue
Relation To Intact Cell
sectioned tissue
Spatial Axis Image Size Pixel Size
X 6000px ——
Y 5509px ——