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*CIL – Cell Image Library accession number. Please use this to reference an image.

CIL:37180*  Cite 
Description

Transmission electron micrograph of rat kidney filtration barrier. Micrograph illustrates the basement membrane between fenestrated capillary endothelium and podocyte foot processes at intermediate magnification. The series of images in this group have particular historic and cell biologic importance for determining the role of the glomerular basement membrane in urinary filtration, especially the charge properties and size selectivity in retention of proteins in the circulation. The images here clearly show the glomerular filtration barrier. The study also elucidated the role of the basement membrane in some forms of nephrosis. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

Technical Details

Relevant citations: Kanwar, Y.S. and M.G. Farquhar. 1979. J. Cell Biol. 81:137-153. Farquhar, M.G., S.L. Wisssig and G.E. Palade. 1961 . J. Exp. Med. 113:47-66. Original 3.25 in. x 4 in. lantern slides were scanned at 600dpi. Original magnification X19,000.

Biological Sources
NCBI Organism Classification
Rattus
Cell Type
kidney cell
glomerular capillary endothelial cell
podocyte
Cellular Component
basement membrane
Biological Context
Biological Process
glomerular filtration
Attribution
Names
Marilyn G. Farquhar
Link
George E. Palade EM Slide Collection
Citation
Digital Object Identifier (DOI)
doi:10.7295/W9CIL37180
Archival Resource Key (ARK)
ark:/b7295/w9cil37180
Grouping This image is part of a group.
Sample Preparation
Methods
osmium tetroxide fixed tissue
Relation To Intact Cell
sectioned tissue
Dimensions
Spatial Axis Image Size Pixel Size
X 6000px ——
Y 5035px ——