Licensing

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Description

This simulation shows a dynamic molecular model of the bacterial cytoplasm, giving us a spectacular glimpse of the crowded conditions of the interior of a cell over a brief 15-microsecond time span. The model includes 50 of the most abundant types of macromolecules reported in Escherichia coli, for a total concentration of 275g/L. This "steric energy" simulation shows a model of macromolecular diffusion based on Brownian dynamics and steric interactions between the molecules. This can be compared the the "full energy" model that also includes electrostatic and hydrophobic interactions.

Biological Sources

NCBI Organism Classification
Escherichia coli
(E. coli)
Cellular Component
cytoplasm

Biological Context

Biological Process
cellular localization

Attribution

Names
Sean McGuffee
Adrian Elcock
Published
PLoS Comput Biol. 2010 Mar 5;6(3):e1000694.
Pubmed
20221255

Grouping

This image is part of a group.

Imaging

Image Type
animation
Data Qualifiers
animation
*CIL – Cell Image Library accession number. Please use this to reference an image.