DRB-treated HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein U1-70K and imaged witb a PicoQuant MicroTime 200 confocal microscope using an Olympus 60x 1.2NA water immersion objective lens. DRB inhibition of transcription results in enlargement and rounding up of splicing factor compartments in which the U1-70K is enriched. From Fig 2C in Huranova et al. 2010 J Cell Biol 191:75-86.
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