Figures 266 (upper left), 267 (upper right), 268 (lower left) and 269 (lower right) from Chapter 8 (Lysosomes) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Autophagic vacuoles from normal rat liver (Fig. 268, by Daniel Friend), and from liver several days after withdrawal of phenobarbital (Figs. 266, 267 and 269, by Robert Bolender). Content in the vacuoles in the upper panels is primarily smooth endoplasmic reticulum and free ribosomes. Vacuoles in the lower panels contain mitochondria and a peroxisome (lower left). A PDF copy of the accompanying chapter is available on the ASCB's BioEDUCATE website.