Stimulated Exocytosis. This micrograph shows the peripheral cytoplasm of a mammotroph in the pituitary of a lactating rat. Several secretion granules are lined up facing the perivascular spaces and a...

The endosomal compartment is enlarged in the ema[1] mutant. Colocalization between DVGLUT (red) aggregates and the endosomal ESCRT protein Hrs (green, also known as Vps27) in motoneuron cell bodies of...

The bottom of the buccal cavity is surrounded by specialized cytoplasm and contains a lip that constricts the opening leading through the cytostome into the receiving vacuole or nascent vacuole. The ...

Vorticella convallaria fixed for EM and buffered in cacodylate. The rough ER is not vesiculated as it is in collidine buffered fixatives but appears as sheets from which Golgi dictyosomes arise. A foo...

As with acidosome fusion with the DV-I, lysosome fusion with the DV-II also seems to occur nearly all at once resulting in a phagolysosome (DV-III) with a highly irregular surface. However, unlike the...

The nascent digestive vacuole forms as the membrane of flattened vesicles fuse with the single membrane of the cytopharynx between the lamellae (2 microtubules forming a lamella) that are connected al...

This image shows the heterogeneity in the content of lysosomes near the plasma membrane between two hepatocytes and near the bile canaliculus (not visible in this field). Some of the lysosomes contai...

High resolution image of an early endosome in planar view that contains HRP-reaction product. This cell was exposed to HRP for 6 min. and then fixed. This early endosome had two small coated evaginati...

Colocalization between DVGLUT (red) aggregates and the endosomal ESCRT protein Hrs (green, also known as Vps27) in motoneuron cell bodies of the ventral nerve cord of a wild-type larva. Wandering thir...

This is one of six images in Figure 6 in Apaja et al., JCB 2010 that shows the fate of various model membrane proteins, that are either folded or in the unfolded state at the plasma membrane, expresse...