3 hr zebrafish embryo labeled with anti-phosphotyrosine antibody (green) and anti-phosphoserine (red). Images made available by Mark Cooper thru The Zebrafish A Living Laboratory.

Expression of transmembrane domain deleted-PINK1-YFP (green) is stabilized in the mitochondira, but does not induce mitochondrial translocation of mCherry-Parkin (red) in PINK1 knock-out mouse embryon...

Expression of R98F PINK1-YFP (green) induces mitochondrial translocation of mCherry-Parkin (red) in the presence of the mitochondrial depolarizing agent CCCP (carbonyl cyanide-m-chlorophenyl hydrazone...

Expression of WT PINK1-YFP (green) does not induce mitochondrial translocation of mCherry-Parkin (red) in PINK1 knock-out mouse embryonic fibroblasts (PINK1 KO MEFs). Transfected PINK1 KO MEFs were tr...

Expression of R98F PINK1-YFP (green), consistent with localization within mitochondria, does not induce mitochondrial translocation of mCherry-Parkin (red). The R98F mutation in PINK1-YFP partially in...

Upon mitochondrial uncoupling, wild-type PINK1-YFP (green) and mCherry-Parkin (red) are localized to mitochondria in PINK1 knock-out mouse embryonic fibroblasts (PINK1 KO MEFs). Transfected PINK1 KO M...

Upon mitochondrial uncoupling, transmembrane domain-deleted PINK1-YFP (green) fails to recruit mCherry-Parkin (red) to mitochondria in PINK1 knock-out mouse embryonic fibroblasts (PINK1 KO MEFs). Tran...

Mouse Embryonic Fibroblasts (MEFs) grown on glass coverslips coated with 10 ug/ml Fibronectin. After 24 hrs cells were fixed in 3% paraformaldehyde and stained with mouse antibody to Paxillin, rabbit...

Localization of Alexa Fluor-594-α-factor-labeled endosomes (red), Abp1-GFP- (green) and Abp140-3GFP- (green) labeled endocytic vesicles. It was possible to distinguish endocytic vesicles from actin c...

Localization of Abp1-RFP (red; left) and Abp140-3GFP (green; center). By expressing Abp1-mRFP and Abp140–3GFP to visualize endocytic vesicles and actin cables respectively, we observed that approxim...