In more extreme cases microfilamentous material builds up into a thick layer surrounding the DV-I membrane as well as the fusion sites between the acidosomes and the DV-I. A similar thick meshwork was...

Electron micrograph of PC12 cells transfected with AP-3 siRNA. PC12 cells were plated onto aclar film discs (Pella) coated with poly-L-lysine, transfected twice with 50 nM AP-3delta1 siRNA and fixed w...

Electron micrograph of PC12 cells transfected with AP-3 siRNA. PC12 cells were plated onto aclar film discs (Pella) coated with poly-L-lysine, transfected twice with 50 nM AP-3delta1 siRNA and fixed w...

Electron micrograph of PC12 cells transfected with AP-3 siRNA. PC12 cells were plated onto aclar film discs (Pella) coated with poly-L-lysine, transfected twice with 50 nM AP-3delta1 siRNA and fixed w...

Contractile vacuole of Nassula sp. Parts of the single CV appear on two sides of the CV pore. Fields of spongiome abut the filled portions of the CV. TEM taken on 3/27/69 by R. Allen with Philips 300 ...

A high resolution image and rare micrograph of the contractile vacuole and intact contractile vacuole membrane of Euplotes. Close examination at high magnification reveals the organization of microtub...

Quick-freeze deep-etch of the contractile vacuole E-fracture face. This face like the collecting canal membrane is porous indicating that many IMPs have been removed from this leaflet during fracturin...

A collecting canal of the contractile vacuole surrounded by smooth spongiome remnants and decorated tubules of the CVC. Microtubules bordering the flattened collecting canal are labeled with immunogol...

A high resolution of some tubules near a contractile vacuole that appear to be decorated with pegs similar to the spongiome of the CV of Paramecium. In Paramecium these pegs are known to be V-type pro...

High resolution image of vesicles and early endosomes under the membranelles of the peniculus of the buccal cavity. Cilia and basal bodies are tangentially fractured in this quick-freeze deep-etch pre...