Starved Dictyostelium cells lacking cGMP-binding protein C (gbpC-; no guanylyl cyclase activity) and in medium supplemented with 60 µM LY294002 (a PI3K inhibitor) and 1µM cAMP migrate toward the ano...

To determine the extent to which extracellular matrix proteins colocalize with the microtubule-anchoring factor LL5s (LL5α), MCF-10A epithelial cells were immunostained with antibodies to laminin rec...

To determine the extent to which extracellular matrix proteins colocalize with the microtubule-anchoring factor LL5s (LL5α), MCF-10A epithelial cells were immunostained with antibodies to the secrete...

Starved cells of a chemotaxis-deficient mutant of Dictyostelium, KI-8 (lacking guanylyl cyclase activity) migrate toward the anode (right) with a slower migration velocity than that of wild-type cells...

Scanning electron microscope image of Strongylocentrotus drobachiensus [sea urchin] at the gastrula stage. Embryo was split open to reveal the blastocoel cavity. There are several migrating mesenchyme...

Localization and intracellular motility of myosin IIB (MIIB) in protrusive regions of migrating CHO.K1 cells. This Video corresponds to Fig. 6 B and video 4 in JCB 183:543-554 , 2008. Images of GFP-MI...

Movie shows actin cytoskeleton in Nck-deficient cells after stimulation with PDGF-B. In the absence of Nck proteins, prominent actin bundles and the almost complete absence of membrane ruffles even af...

To determine the extent to which extracellular matrix proteins colocalize with the microtubule-anchoring factor LL5β, MCF-10A epithelial cells were immunostained with antibodies to the secreted autoc...

Scanning electron microscope image of Strongylocentrotus drobachiensus embryo at the primary mesenchyme blastula stage. Embryo was split open to reveal the outer epithelial layer and the blastocoel ca...

Movie shows actin cytoskeleton in Nck-deficient cells rescued with Nck1 after stimulation with PDGF-B. In the presence of Nck1, PDFG-B stimulation induced, in addition to peripheral ruffles, very noti...