Fluorescence images of Hela cells treated sequentially with nocodazole ant Taxol showing the distribution of beta-tubulin (blue), and nuclear mitotic apparatus protein (NuMA)or human structural maintenance of chromosomes (hSMC) protein (red). DAPI-stained DNA is shown in black and white. Cells were observed with an Olympus IX70 microscope and recorded with a Magnaview CCD camera. See Fig 2B in Kong et al., 2009, Mol Biol Cell 20:1289-1301.