Peroxisomes in cultured rat hepatocytes have proliferated under treatment with 4-phenylbutyrate. The animal was transgenic for PPARalpha -/-, so phenyl butyrate acts without the PPAR receptor.

Figure 182 from Chapter 5 (Endoplasmic Reticulum) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Electron micrograph of liver from a hamster treated with phenobarbitol for four days. Chronic exposure...

Gap junctions isolated from mouse liver and negatively stained with uranyl formate. At higher magnification, the 8-9 nm particles, or connexons, have a central 1.5-2 nm electron dense pore. Images b...

Figures 286 (upper) and 287 (lower) from Chapter 9 (Peroxisomes) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Peroxidase stained tissue from rat liver showing the normal size and distribution of per...

Figure 363 from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. A portion of a liver cell from the slender salamander, Batrachoseps attenuatus. This striking exampl...

Transmission electron micrograph of the junctional complexes at the intersection of three hepatocytes. This image was taken from liver tissues from an ethanol fed rat and also shows the bile canalic...

Transmission electron micrograph of liver from a 1-day old rat showing mitochondria, rough endoplasmic reticulum and rosettes of glycogen granules. Image made available by James D. Jamieson and the De...

Transmission electron micrograph of a thin section of the liver of a 1-day old rat showing a grazing view of rough endoplasmic reticulum (RER, sometimes termed granular endoplasmic reticulum. The 'rou...

Figure 349 from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Electron micrograph of an hepatic cell from a fasted hamster after an injection of cortisone. In mam...

Upper: a gap junction on the boundary between two hepatic cells shows a typical narrow and straight interface. Lower: in some preparations, gap junctions appear curved, and project into one of the ce...