Shown are a normal human fibroblasts stained for lamin A (red), a major component of the nuclear lamina. Other images in this group show the envelope abnormalities that occur in HGPS patients carryin...

Confocal microscope image of a mouse fibroblast cell about to divide. The nuclei are stained red, and the actin and tubulin filaments of the cytoskeleton, forming the internal framework, are stained g...

High voltage (1MeV) transmission electron microscopy image of an isolated metaphase chromatid pair from a mouse A9 cultured cell, showing the fiber-like structure and several pieces of attached membra...

High voltage (1MeV) transmission electron microscopy image of an isolated metaphase chromatid pair from a mouse A9 fibroblast, showing the fiber-like structure. The image was taken with a specimen til...

High voltage (1MeV) transmission electron microscopy image of an isolated metaphase chromatid pair from a mouse A9 cell, showing the fibrous structure. The image was taken with a specimen tilt of 55 d...

Digital multi-color immuno fluorescence microscopy and phase contrast image of fibroblast cells in culture stained with various antibodies. The Phase contrast (green) image was overlayed over the micr...

Confocal micrograph of NIH-3T3 cells co-transduced with 5 fluorescent proteins. The cells were marked by co-transduction with Lentiviral Gene Ontology (LeGO) vectors expressing Cerulean (cyan), EGFP ...

Behavior of a patient-derived human fibroblast line (PD-NC4) containing a mutated chromosome 4 in which the normal centromere is epigenetically silenced and a neo-centromere has formed 25 Mbp down the...

Association of plectin with myosin II. Platinum replica of nocodazole and treated REF-52 cell with actin depleted by gelsolin and plectin labeled with immunogold (10 nm). Individual plectin molecules...

Mouse 3T3 fibroblast stained for the nucleolar protein nucleostemin (left, green) and 28S rRNA (right, red).