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Confocal micrograph of a mast cell in human eye with conjunctivitis. This image shows a single mast cell invading conjunctival tissue in response to an inflammatory agent or pathogen. The mast cell contains vesicles of histamine (red dots). Mast cells are among the first cells of the immune system to react to the presence of an invading pathogen and they facilitate the movement of leukocytes (white blood cells) and other immune cells toward the site of infection. The image is composed of 42 stacked sections. Honorable Mention, 2011 Olympus BioScapes Digital Imaging Competition®.

Technical Details

Biological Sources

NCBI Organism Classification
Homo sapiens
Cell Type
mast cell
Cellular Component

Biological Context

Biological Process
histamine secretion involved in inflammatory response
Human Disease
acute conjunctivitis


Donald Pottle
2011 Olympus BioScapes Digital Imaging Competition®
2011 Olympus BioScapes Digital Imaging...
The Schepens Eye Research Institute, Boston, MA, USA


Image Type
recorded image
Imaging Mode
confocal microscopy
Visualization Methods
visualization of contiguous regions

Sample Preparation

Relation To Intact Cell
whole mounted tissue


Spatial Axis Image Size Pixel Size
X 2048px ——
Y 2048px ——
*CIL – Cell Image Library accession number. Please use this to reference an image.