Licensing

Attribution_by_nc_nd
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Description

Confocal micrograph of a mast cell in human eye with conjunctivitis. This image shows a single mast cell invading conjunctival tissue in response to an inflammatory agent or pathogen. The mast cell contains vesicles of histamine (red dots). Mast cells are among the first cells of the immune system to react to the presence of an invading pathogen and they facilitate the movement of leukocytes (white blood cells) and other immune cells toward the site of infection. The image is composed of 42 stacked sections. Honorable Mention, 2011 Olympus BioScapes Digital Imaging Competition®.

Technical Details

Biological Sources

NCBI Organism Classification
Homo sapiens
(human)
Cell Type
mast cell
Cellular Component
histamine

Biological Context

Biological Process
histamine secretion involved in inflammatory response
Human Disease
acute conjunctivitis

Attribution

Names
Donald Pottle
2011 Olympus BioScapes Digital Imaging Competition®
Link
2011 Olympus BioScapes Digital Imaging...
Other
The Schepens Eye Research Institute, Boston, MA, USA

Imaging

Image Type
recorded image
Imaging Mode
confocal microscopy
Visualization Methods
visualization of contiguous regions

Sample Preparation

Relation To Intact Cell
whole mounted tissue

Dimensions

Spatial Axis Image Size Pixel Size
X 2048px ——
Y 2048px ——
*CIL – Cell Image Library accession number. Please use this to reference an image.