Transmission electron micrograph of an electron-lucent vacuole from a sertraline-treated BY4716 wildtype cell. (31,500X). This image is part of a group of yeast vacuole images (CIL:40437-40448).
This group of images contains representative whole-cell images and high-magnification zooms of organelle structures of interest. All cells were grown in liquid rich media (YPD pH6.5) at 30C with aerated shaking, and cultures were sampled in mid-logarithmic phase. Treated cells were exposed to 60µM antidepressant sertraline (Zoloft®) for 45 minutes.