The Cell: An Image Library - Image CIL:38917

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CIL:38917^*

Description

Confocal micrograph of cultured colon cancer cells showing the nuclei stained with DAPI in blue, the actin cytoskeleton in red and plectin (isoform 1k) in green. Plectin interacts with cytoskeletal actin, affecting its behaviour. This subtype of plectin promotes the migration of cells and may affect metastasis.

Technical Details

B0006844 Confocal micrograph 2005 Collection: Medical Photographic Library Wellcome Images. Image copyrighted. Please see details at http://creativecommons.org/licenses/by-nc-nd/2.0/uk/

Biological Sources

Cell Type: colon cancer cell
Cellular Component: actin cytoskeleton; plectin; nucleus

Biological Context

Biological Process: cell migration
Human Disease: intestinal cancer; metastatic tumor to the colon

Attribution

Link: Wellcome Images
Other: Lorna McInroy

Imaging

Image Type: recorded image
Imaging Mode: confocal microscopy
Parameters Imaged: fluorescence emission
Source of Contrast: distribution of epitope
Visualization Methods: 4',6-diamidino-2-phenylindole (DAPI)
Processing History: unprocessed raw data

Sample Preparation

Methods: chemically fixed tissue
Relation To Intact Cell: dispersed cells in vitro

Dimensions

Spatial Axis	Image Size	Pixel Size
X	550px	——
Y	576px	——
Channel	Wavelength
1	μm

*CIL – Cell Image Library accession number. Please use this to reference an image.