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CIL:38802*  Cite 

This confocal micrograph shows the detailed structure of the retina from a one-month-old mouse. The retina is the photoreceptive organ of the eye. It is composed of layers of neuronal cells that capture and transmit the light information, converting it into electrical signals that the brain can interpret. Fluorescent markers have been used to highlight different classes of these cells within the retina. Green staining highlights glial cells, which act as neuronal supporting cells and produce myelin, the protective conductive layer that surrounds the axons of the neurons. The red fluorescently labelled protein marks astrocytes, star-shaped glial cells that provide nutrients to developing neurons and regulate neuronal activity. The blue fluorescence marks cell nuclei. This image was created as part of a study to examine the stress observed in the retina as a result of oxygen deprivation. These studies are helping scientists to understand why premature babies develop retinal disease when born too early. 2011 Wellcome Images Award winner.

Technical Details

Due to the large size of the whole structure, this images was composed of multiple z stack images 'stitched' together to show the whole structure. One side was then reflected, to create the perfect symmetry of the whole retina that you see in the image. B0007750 Confocal micrograph Collection. Copyrighted work available under Creative Commons by-nc-nd 2.0 UK: England & Wales, see

Biological Sources
NCBI Organism Classification
Mus musculus
Cell Type
glial cell
retinal cell
Cellular Component
Biological Context
Biological Process
neural retina development
Freya Mowat
Wellcome Images
Digital Object Identifier (DOI)
Archival Resource Key (ARK)
Image Type
recorded image
Image Mode
confocal microscopy
Parameters Imaged
fluorescence emission
Source of Contrast
distribution of a specific protein
Processing History
image reflected
Sample Preparation
Relation To Intact Cell
whole mounted tissue
Spatial Axis Image Size Pixel Size
X 554px ——
Y 576px ——