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*CIL – Cell Image Library accession number. Please use this to reference an image.

CIL:37181*  Cite 

Transmission electron micrograph of rat kidney filtration barrier. Image is low magnification vies of the basement membrane filtration slits, urinary space, and the glomerular filtration capillary lumen. The series of images in this group have particular historic and cell biologic importance for determining the role of the glomerular basement membrane in urinary filtration, especially the charge properties and size selectivity in retention of proteins in the circulation. The images here clearly show the glomerular filtration barrier. The study also elucidated the role of the basement membrane in some forms of nephrosis. Image made available by James D. Jamieson and the Department of Cell Biology, Yale University School of Medicine.

Technical Details

Relevant citations: Kanwar, Y.S. and M.G. Farquhar. 1979. J. Cell Biol. 81:137-153. Farquhar, M.G., S.L. Wisssig and G.E. Palade. 1961 . J. Exp. Med. 113:47-66. Original 3.25 in. x 4 in. lantern slides were scanned at 600dpi.

Biological Sources
NCBI Organism Classification
Cell Type
kidney cell
glomerular endothelial cell
Cellular Component
basement membrane
Biological Context
Biological Process
glomerular filtration
Marilyn G. Farquhar
George E. Palade EM Slice Collection
Digital Object Identifier (DOI)
Archival Resource Key (ARK)
Grouping This image is part of a group.
Sample Preparation
osmium tetroxide fixed tissue
Relation To Intact Cell
sectioned tissue
Spatial Axis Image Size Pixel Size
X 6000px ——
Y 4882px ——