HeLa cells stably expressing BAC-encoded GFP-labeled snRNP protein hPrp8 and imaged witb a Leica SP5 confocal microscope using a 60x 1.4NA HCX Plan Apo objective lens. The hPrp8 is confined to the nucleoplasm and enriched in splicing factor compartments and Cajal Bodies (bright dots). See Fig 1A in Huranova et al. 2010 J Cell Biol 191:75-86.
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